Late Night Guests – April 21, 2026

Trump Claims He Would’ve Been Better at War Than Other Presidents, Fails at His Own Iran Peace Plans

Jimmy Celebrates Webby Wins and MAD Magazine Cover | The Tonight Show Starring Jimmy Fallon

Leonardo DiCaprio Sent Nikki Glaser Baskets of Pasta After the Golden Globes (Extended)

#NikkiGlaser breaks down the Alix vs. Alex drama 😭 #FallonTonight

Jesse Tyler Ferguson Went to a Gentlemen’s Club Thinking It Was Pilates (Extended) | Tonight Show

#JesseTylerFerguson accidentally showed up to a gentlemen’s club 😭 #FallonTonight

Ella Stiller Got to Sit at the Friends Fountain with Lisa Kudrow (Extended) | The Tonight Show

Isabel Hagen Stand-Up: Marriage, Camping | The Tonight Show Starring Jimmy Fallon

"I Think Aliens Would Report Back: No Sign Of Intelligent Life On Earth" - Neil deGrasse Tyson

The Intense Bromance Between Neil deGrasse Tyson and William Shatner Continues

"Joy" - RAYE feat. Amma & Absolutely (LIVE on The Late Show)

"Click Clack Symphony" - RAYE (LIVE on The Late Show)

John Kerry's Advice To Trump's Iran Negotiators: Take Time To Be Reasonable

Trump Extends Iran Ceasefire Again, Reads from Bible & Tucker Carlson Apologizes for Supporting Him

Jon Favreau on The Mandalorian & Grogu, Directing Scorsese & Casting Robert Downey Jr. as Iron Man

James Taylor on Performing at 15, The Beatles Launching His Career & Elvis Covering One of His Songs

James Taylor – That’s Why I’m Here

Seth Holds a Surprise Inspection of His Monologue Writers in April 2026

Aubrey Plaza Asks Seth to Deliver Her Baby, Talks About Her Mafia Kittens with Butthole Issues

Aubrey Plaza loves to attend a WNBA draft 🏀

Gaten Matarazzo on Life After Stranger Things and His Mind-Blowing Stoner Film Pizza Movie

Gaten Matarazzo’s plan to be incognito at the "Stranger Things" finale backfired 😂

Dan Bucatinsky's The Comeback Is Making a Comeback Thanks to the Threat of AI

Dan Bucatinsky talks about the "The Comeback" and its unusual filming schedule

Kash Patel Denies Excessive Drinking & Labor Sec.’s Family Plays HR Violation Bingo | The Daily Show

Noah Wyle - Capturing the Human Experience on “The Pitt” | The Daily Show