Jimmy Fallon Guests April 21, 2026

Episode clips

Nikki Glaser

Leonardo DiCaprio Sent Nikki Glaser Baskets of Pasta After the Golden Globes (Extended)

#NikkiGlaser breaks down the Alix vs. Alex drama 😭 #FallonTonight

Jesse Tyler Ferguson

Jesse Tyler Ferguson Went to a Gentlemen’s Club Thinking It Was Pilates (Extended) | Tonight Show

#JesseTylerFerguson accidentally showed up to a gentlemen’s club 😭 #FallonTonight

Ella Stiller

Ella Stiller Got to Sit at the Friends Fountain with Lisa Kudrow (Extended) | The Tonight Show

Isabel Hagen

Isabel Hagen Stand-Up: Marriage, Camping | The Tonight Show Starring Jimmy Fallon

Other episode clips

Trump Claims He Would’ve Been Better at War Than Other Presidents, Fails at His Own Iran Peace Plans

Jimmy Celebrates Webby Wins and MAD Magazine Cover | The Tonight Show Starring Jimmy Fallon

FAQ

Who were the guests on The Tonight Show Starring Jimmy Fallon on Apr 21, 2026?

Nikki Glaser, Jesse Tyler Ferguson, Ella Stiller, and Isabel Hagen were the guests on this episode.

When did this episode air?

Apr 21, 2026.