Jimmy Fallon Guests April 21, 2026

Episode clips

Nikki Glaser

Nikki Glaser discusses her Coachella voice loss, Leonardo DiCaprio’s pasta gift, and the celebrity and dating stories that become material for her comedy.

Interview

Leonardo DiCaprio Sent Nikki Glaser Baskets of Pasta After the Golden Globes (Extended)

Nikki Glaser discusses losing her voice at Coachella, Leonardo DiCaprio sending her baskets of pasta after the Golden Globes, and the dating and celebrity stories that become material for her comedy.

#NikkiGlaser breaks down the Alix vs. Alex drama 😭 #FallonTonight

Jesse Tyler Ferguson

Jesse Tyler Ferguson recounts mistaking a gentlemen’s club for a Pilates studio and discusses family life and turning fifty.

Interview

Jesse Tyler Ferguson Went to a Gentlemen’s Club Thinking It Was Pilates (Extended) | Tonight Show

Jesse Tyler Ferguson recounts accidentally going to a gentlemen’s club believing it was a Pilates studio and discusses turning the embarrassing mix-up into a story. He also talks about family life and reaching his fiftieth birthday.

#JesseTylerFerguson accidentally showed up to a gentlemen’s club 😭 #FallonTonight

Ella Stiller

Ella Stiller reflects on growing up in New York, visiting the Friends fountain with Lisa Kudrow, and the unusual experiences of growing up in a famous family.

Interview

Ella Stiller Got to Sit at the Friends Fountain with Lisa Kudrow (Extended) | The Tonight Show

Ella Stiller discusses growing up in New York, visiting the Friends fountain with Lisa Kudrow, and the unusual experiences that came with being the daughter of Ben Stiller and Christine Taylor.

Isabel Hagen

Isabel Hagen performs stand-up about marriage, camping, and the awkward assumptions of everyday social life.

Other

Isabel Hagen Stand-Up: Marriage, Camping | The Tonight Show Starring Jimmy Fallon

Isabel Hagen performs stand-up about marriage, camping, unwanted compliments, and the awkward assumptions people make in everyday social situations. Her set comes from Isabel Hagen at the Bitter End.

Other episode clips

Monologue

Trump Claims He Would’ve Been Better at War Than Other Presidents, Fails at His Own Iran Peace Plans

Jimmy Fallon jokes about Trump’s claims on Iran, the stalled ceasefire, and the administration’s political messaging, while also mocking the president’s confidence that he would have handled past wars better.

Monologue

Jimmy Celebrates Webby Wins and MAD Magazine Cover | The Tonight Show Starring Jimmy Fallon

Jimmy Fallon celebrates the Tonight Show’s six Webby Awards and its MAD Magazine cover, thanking the digital team and joking about the show’s online success.

FAQ

Who were the guests on The Tonight Show Starring Jimmy Fallon on Apr 21, 2026?

Nikki Glaser, Jesse Tyler Ferguson, Ella Stiller, and Isabel Hagen were the guests on this episode.

When did this episode air?

Apr 21, 2026.